Document 0583
 DOCN  M9480583
 TI    Oral medicine.
 DT    9410
 AU    Bissell TA; Doppalapudi VA; Department of Periodontology, Harvard School
       of Dental Medicine,; Boston, MA 02115.
 SO    Curr Opin Periodontol. 1994;:54-63. Unique Identifier : AIDSLINE
       MED/94305644
 AB    The practice of dentistry requires an understanding of medical illnesses
       and the implications of treatment on the oral environment. Periodic
       review enables the practitioner to anticipate patient needs and to
       interact competently with other medical care providers. Presented in
       this review are recent advances in understanding the relationship
       between medical and oral diseases. Where appropriate, therapeutic
       regimens for the treatment of oral manifestations are suggested.
       Diabetes remains equivocally associated with periodontal disease. The
       dynamic nature of the immune system and the exhaustive list of oral
       microbial flora have led to immense and promising research in
       understanding the pathogenesis of periodontal diseases. It is
       anticipated that this would lead to methodologies that could modulate
       the mechanisms of host response and thereby regulate, for example, bone
       resorption in inflammatory periodontal diseases. HIV-associated
       periodontal and other oral manifestations have provoked challenging
       goals in efficient treatment of these patients. The survival time of
       cancer patients continues to lengthen, resulting in significant numbers
       of affected individuals. Treatment modalities, chiefly radiation and
       chemotherapy, produce marked effects on the oral tissues. The
       detrimental oral consequences of oncologic therapy can be reduced with
       proper patient education and attention to prophylactic measures.
       Neoplasia occurs within the oral environment often mimicking
       inflammatory disease. Systemic diseases may manifest orally and may be
       subtle in presentation. The dentist is compelled to evaluate all lesions
       of the oral tissues with the expectation that they may be a lesser sign
       of a more severe condition.
 DE    Antineoplastic Agents/ADVERSE EFFECTS  Cranial Irradiation/ADVERSE
       EFFECTS  Diabetes Mellitus/COMPLICATIONS  Gingival Neoplasms  Head and
       Neck Neoplasms/RADIOTHERAPY  Human  HIV Infections/COMPLICATIONS
       *Periodontal Diseases/ETIOLOGY/IMMUNOLOGY  Periodontium/DRUG
       EFFECTS/RADIATION EFFECTS  Virus Diseases/COMPLICATIONS  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).